Affect of restrictive bariatric surgery on levels of vaspin in morbidly obese subjects    Decreased levels of vaspin early after laparoscopic restrictive bariatric surgery is more likely due to decreased dietary intake

Insulin detemir in a twice daily insulin regimen versus a three times daily insulin regimen in children with type 1 diabetes    Incorporating long acting insulin analogue in a twice daily regimen is a viable and more simplified option which may improve compliance in T1DM children.

Me-Can cohort study: An increased risk of high-grade glioma was found for diastolic blood pressure and triglycerides    1312 primary brain tumours diagnosed during follow-up were predominantly meningioma (n=348) and high-grade glioma (n=436).

The PARTAGE study: prevalence of orthostatic hypotension and its association with blood pressure, arterial stiffness, cardiovascular and metabolic disorders and medication in individuals aged > 80 years living in nursing home    A lower prevalence of orthostatic hypotension was reported in treated hypertensive patients with SBP ≤ 140 mmHg than patients with SBP > 140 mmHg.

Higher serum sclerostin levels in type 2 diabetics specifically contributes to the detrimental effect of thiazolidinediones on bone    Serum sclerostin levels increased by 11% in pioglitazone -treated patients after 24 weeks treatment and decreased by 1.8% in metformin -treated patients

Besides gestational age the most significant predictor of infant birth weight is maternal weight at screening    Maternal birth weight, BMI at 20 years of age and maximal BMI correlated significantly with newborn birth weight, newborn length and with infant weight eight weeks later in all women.

Affect of lifestyle interventions on dyslipidemia in women of reproductive age    Most guidelines recommended dyslipidemia screening every 5 years

Metabolic substudy of ANRS COPANA cohort: severe immune deficiency in antiretroviral therapy -naive patients as an early risk factor for altered insulin sensitivity    Low CD4 (+) T-cell count was an independent risk factor for altered insulin sensitivity (CD4 (+) T-cell count >500/mm³ as the reference) in addition to older age and higher BMI.

Association of accuracy of duplex scanning with arteriography when performed at vascular "dedicated" or "nondedicated" facilities, among diabetic patients with critical limb ischemia    significantly higher diagnostic accuracy pertaining to the examination of the infrapopliteal arteries was observed in diabetic patients with duplex scanning

Twice daily versus multiple daily insulin injections in children with type 1 diabetes    Children started on MDI show better mean improvement in HbA1c at 12 months than started on started on BD insulin

Risk of hypoglycemia in critically ill children may increase by the disruptions in carbohydrate metabolism    Best accomplishment of the prevention of hypoglycemia, especially in the setting of intravenous insulin use is achieved by the combination of accurate measuring techniques, frequent or continuous glucose monitoring, and computerized insulin titration protocols

ADDITION study (Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen Detected Diabetes in Primary Care): correlation between heart rate and heart rate variability measurements by the computer-assisted and manually based methods    Correlation, r values of Pearson's obtained on comparing results from the two methods: 0.98 for heart rate, 0.76 for SDNN and 0.68 for RMSSD.

Breath-based lipid test study reveals strong correlations between measured and predicted values during both lipid suppression and lipid infusion studies    Measured and predicted triglycerides and free fatty acids values also displayed very strong statistical agreement in this most accurate common prediction model.

Major display of a triad of recent onset diabetes with significant weight loss and jaundice or dilated common bile duct without any obvious cause in pancreatic cancer patients    124/167 pancreatic cancer patients displayed recent onset diabetes (<1yr), all of whom were non obese and either had jaundice or a dilated v without any other cause apart from abdominal symptoms

Hyperglycemic clamp study: Inverse relationship between insulinemia and time to maximum perfusion during post occlusive reactive hyperemia in type 1 diabetics    Higher maximum perfusion and higher velocity of perfusion increase during PORH were reported in hyperglycemia compared to baseline.

Affect of baseline Hemoglobin A1C on efficacy of Liraglutide and other anthiyperglycemic therapies    Reductions in A1C levels are generally greater in groups with higher baseline A1C values irrespective of treatment

Italian Diabetes and Exercise Study (IDES): Exercise volume, study arm and inversely baseline score were the independent correlates of improvements in both physical component summary and mental component summary    A trend for increasing quality of life with increasing exercise volume with significant improvement of the physical component summary measure only above 17.5 metabolic equivalents h -1 week -1 and a clear volume-relationship were reported for the mental component summary measure in the exercise group.

The PREdiction of Metabolic Syndrome in Adolescence (PREMA) Study: prediction of MetS among adolescents of the validation cohort with sensitivity 91% and specificity 98%    105 adolescents in the derivation phase were diagnosed with MetS, whereas diagnosis of MetS in adolescence was independently associated with birth weight <10th percentile, birth head circumference <10th percentile and parental overweight or obesity (at least in one parent).

Significantly greater walking palmitate storage in lower-body subcutaneous fat among women    Similar upper body subcutaneous palmitate storage was reported during walking between sexes, while greater lower-body subcutaneous storage was reported in women than men.

Diabetic retinopathy doubles the frequency of blindness    Twice as frequent prevalence of blindness was reported in patients with diabetic retinopathy when compared to those without it.

A simple, brief integrated approach to depression and type 2 diabetes treatment improves adherence to oral hypoglycemic agents and antidepressant medications, glycemic control and depression among primary care patients    More likely to achieve HbA 1c levels of < 7% and remission of depression (PHQ-9 score of < 5) was reported in patients who received the intervention as compared to patients in the usual care group at 12 weeks

High prevalence of pre-diabetes in adults treated with antipsychotic drugs    Highly prevalent pre-diabetes is reported in adults treated with antipsychotic drugs which correlate with markers of increased intra-abdominal adiposity, enhanced lipolysis and insulin resistance.

Effects of short-term administration of liraglutide on visceral fat adiposity, appetite, and food preference    Liraglutide significantly improves the scores of eating behavior, food preference and the urge for fat intake

Extremely obese children and adolescents at high risk of future weight gain and potentially reduced response to weight-loss interventions    Significantly higher levels of leptin were reported by extremely obese than obese, overweight and normal weight.

Noninsulin treatment of type 2 diabetes mellitus geriatric patients    Prevalence of hypoglycemia is high with the administration of secretagogues, sulfonylureas and glinides

Renal biopsy should be considered in type 2 diabetics with nephropathy    Presence of acute renal failure and microscopic hematuria are the useful clinical markers for non-diabetic renal diseases.

Homocysteine and bilirubin may be useful biomarkers for increased risk of diabetic retinopathy    Incidence of diabetic retinopathy was statistically and significantly associated with the duration of DM, age, fasting blood glucose, urine albumin-creatinine ratio, plasma homocysteine level, duration of DM and total bilirubin level in multiple logistic regression analysis.

Higher self-rating depression scale and higher Pittsburgh sleep quality index in diabetics    Higher Pittsburgh Sleep Quality Index was reported in diabetic patients with neuropathy and higher Self-Rating Depression Scale was reported in diabetic patients with advanced retinopathy.

Collaborative, team-based and care management program for complex patients (TEAMcare):    Pharmacotherapy initiation and adjustment rates were sixfold higher for antidepressants, threefold higher for insulin and nearly twofold higher for antihypertensive medications among TEAMcare as compared to usual care patients.

Higher prevalence of diabetes among people with a lifetime diagnosis of schizophrenia or psychosis    A clear increase in the probability of having diabetes was reported as the number of psychotic symptoms increased after controlling for different potential confounders.

Glycemic control improvement by the addition of metformin to insulin therapy shortly after resolution of diabetic ketoacidosis in obese children with diabetic ketoacidosis    Lower HbA1c levels, higher rates of near-normoglycemia remission and lower frequency of diabetic ketoacidosis recurrence were observed by the addition of metformin to insulin therapy shortly after resolution of diabetic ketoacidosis.

DIAB-CORE Consortium: higher prevalence of type 2 diabetes in men than in women and highest regional standardized prevalence in the East Germany    Among persons with Type 2 diabetes, more frequent treatment with oral antidiabetic agents was reported in the south and less in the northeast, whereas more frequent treatment with insulin alone was reported in the northeast than in the south.

Additional benefit of flavonoids to standard drug therapy in managing CVD risk in postmenopausal type 2 diabetic patients    The combined flavonoid intervention resulted in a significant reduction in estimated peripheral insulin resistance and improvement in insulin sensitivity.

Effect of statins on exercise-induced muscle injury    Susceptibility to exercise-induced muscle injury with statins increases with age

Factors influencing health-related quality of life in patients with and without diabetic foot ulcers    Among diabetic patients without foot ulcers, male gender score higher in all domains of quality of life than female gender