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The relationship between vasoconstrictor changes in foot arteries and autonomic neuropathy in diabetic patients The study showed that %RI of the digital artery is a useful and reliable sympathetic function test of early phase in diabetic patients.



Comparative study of transcardiac utilization of adiponectin in patients with and without type 2 diabetes As compared to nondiabetic patients, diabetic patients have a decreased adiponectin level in the basal state and an impaired utilization of adiponectin in the coronary artery/heart



The relationship between the TNF-�-C-857T polymorphism and LDL cholesterol levels according to statin treatment in type 2 diabetics Te mutant allele of the C-857T promoter polymorphism of the TNF-� gene may predispose to resistance to the LDL cholesterol�lowering effect of statins



Long-term efficacy of co-administration of prescription omega-3-acid ethyl esters and simvastatin in hypertriglyceridemic patients P-OM3 produced sustained reductions in non-HDL-C levels in simvastatin-treated patients with TG levels between 200 and 500 mg/dL



Significant improvements in peripheral insulin sensitivity was reported following a 1-year diet and exercise intervention in patients with type 2 diabetes Changes in overall weight and hepatic fat were the most important determinants of metabolic improvements



Critical role of caveolin-enriched domain of the plasma membrane Ceramide can switch from a PKC�-dependent mechanism to a PP2A pathway, acting negatively on PKB/Akt



Intestinal apoB48-containing lipoprotein production is acutely suppressed by insulin in humans This may involve insulin's direct effects and insulin-mediated suppression of circulating FFAs



Restoration of mitochondrial function and insulin sensitivity with exercise training in patients with type 2 diabetes The study showed that increased capacity to store IMCL and restoration of improved mitochondrial function contribute to improved muscle insulin sensitivity.



Association of Gestational weight gain to adulthood obesity Greater gestational weight gain is associated with an increased BMI in childhood through adulthood and with an increased risk of obesity in adults



Prevalence and estimated probability of undiagnosed diabetes in different ethnic groups with obesity Prevalence of undiagnosed diabetes increased with an increasing BMI or waist circumference to a similar degree in men in all ethnic groups but to a lesser degree in Asian Indian women than in others.



Mechanism underlying the association of Lipocalin-2 to insulin resistance and obesity Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in insulin resistant subjects



Quantitative assessment of insulin resistance in Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study The combined analysis SNPs had admixture-adjusted p values of p ADD=0.00010�0.0020 with 8 to 41% differences in genotypic means for SI and DI



Association of increased size of adipose cells with localised inflammation in weight-stable, moderately obese humans The researchers showed that an increased proportion of small adipose cells is associated with inflammation in subcutaneous adipose tissue



MI was significantly associated with �GLP-1 in elderly men with type 2 diabetes mellitus group but not in the IGT or NGT groups The study also showed that impaired glucagon-like peptide-1 secretion is associated with IGT, but not with type 2 diabetes mellitus, in elderly men



Relevance of low circulating levels of adiponectin and increased leptin to GDM and subsequent diabetes Hypoadiponectinaemia during pregnancy predicts postpartum insulin resistance and beta cell dysfunction